Bleiweiss expects cards bearing #1, #69, #420 and #500 to be the most expensive, followed by "#2-#9, #13, #187, #404 and #411
I know for a fact that I and many other collectors would be more invested if we knew we were guaranteed one of the 12 alternate art cards in each sealed booster
The blue Defiler is arguably one of the better ones
Artist-themed singles
There are other fun little details, like the serialized Chocobo cards that come in five different colors

New Creature Types in Each Set/Block Lorwyn : Noggle Magic 2010 : Siren Zendikar : Ally, Surrakar, Eldrazi Scars of Mirrodin : Hippogriff, Germ, Praetor Innistrad : Werewolf Theros : God, Sable, Lamia, Nymph Khans of Tarkir : Naga Battle for Zendikar : Scion, Processor Shadows over Innistrad : Mole Kaladesh : Aetherborn, Pilot, Servo, Monkey Amonkhet : Jackal Ixalan : Trilobite, Dinosaur Battlebond : Azra Core Set 2019 : Egg War of the Spark : Army Commander 2019 : Sculpture Throne of Eldraine : Mouse, Peasant, Warlock, Noble Theros Beyond Death : Demigod, Tentacle Ikoria: Lair of Behemoths : Otter, Shark Core Set 2021 : Dog Kaldheim : Phyrexian Strixhaven: School of Mages : Inkling, Fractal Modern Horizons 2 : Ranger, Phyrexian creature type update Dungeons & Dragons: Adventures in the Forgotten Realms : Bard, Beholder, Gnoll, Halfling, Hamster Tiefling The Lost Caverns of Ixalan : Capybara, Llama, Snail Outlaws of Thunder Junction : Armadillo, Mount, Coyote, Porcupine, Possum, Varmint Bloomburrow : Skunk, Weasel Duskmourn: House of Horror : Glimmer, Toy, Final Fantasy : Moogle, Qu, Edge of Eternities: Drix, Lobster Spider-Man : Symbiote, Villain Universes Beyond: Echidna, Hero Some creature types have also been removed over the years
