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Ann N Y Acad Sci 1259:95103
Increased Self-Esteem and Confidence: Positive impact on mental health and body image
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The STEP 1 trial, for example, reported an average weight loss of 14.9% in participants receiving semaglutide, compared to just 2.4% in the placebo group
Enhancing Functional Capacity Without proper training, patients may notice a decline in their ability to perform everyday tasks that require force outputlike rising from a low chair, lifting a child, or walking up an incline
It is reasonable to take both observations seriously as hypotheses, with two cautions: Phase 2 trials are smaller, and the trial populations are not identical to GLP-1 trial populations
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